Swee Lay Thein Selected Research

Fetal Hemoglobin (Hemoglobin F)

7/2018	MYB - A regulatory factor in hematopoiesis.
1/2018	Molecular basis of β thalassemia and potential therapeutic targets.
1/2018	A ten year review of the sickle cell program in Muhimbili National Hospital, Tanzania.
1/2018	g(HbF): a genetic model of fetal hemoglobin in sickle cell disease.
9/2017	Fetal Hemoglobin is Associated with Peripheral Oxygen Saturation in Sickle Cell Disease in Tanzania.
1/2017	Genetic Basis and Genetic Modifiers of β-Thalassemia and Sickle Cell Disease.
2/2015	Genetic association of fetal-hemoglobin levels in individuals with sickle cell disease in Tanzania maps to conserved regulatory elements within the MYB core enhancer.
1/2015	Genetic variants at HbF-modifier loci moderate anemia and leukocytosis in sickle cell disease in Tanzania.
1/2014	Genome wide association study of fetal hemoglobin in sickle cell anemia in Tanzania.
1/2013	Genetic association studies in β-hemoglobinopathies.

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Swee Lay Thein Research Topics

Disease

62	Sickle Cell Anemia (Hemoglobin S Disease) 04/2024 - 03/2005
11	Thalassemia 01/2022 - 03/2011
9	Anemia 01/2022 - 04/2010
8	Inflammation (Inflammations) 06/2021 - 10/2007
8	Hemolysis 01/2021 - 03/2005
8	beta-Thalassemia (Cooley's Anemia) 07/2018 - 01/2005
6	Acute Pain 10/2022 - 10/2007
6	Pain (Aches) 10/2022 - 08/2015
6	Iron Overload 01/2022 - 03/2011
5	Hemoglobinopathies 01/2021 - 07/2007
3	Sickle Cell Trait 04/2024 - 12/2006
3	Thrombosis (Thrombus) 01/2021 - 11/2017
3	Hemolytic Anemia 01/2021 - 10/2011
3	Hemochromatosis (Bronze Diabetes) 05/2010 - 01/2009
2	Necrosis 01/2020 - 08/2009
2	Infarction (Infarctions) 01/2018 - 01/2018
2	Stroke (Strokes) 01/2018 - 03/2011
2	Genetic Risk Score 01/2018 - 01/2017
2	Reticulocytosis 09/2017 - 02/2011
2	Cyanosis 03/2017 - 02/2011
2	Chronic Kidney Failure (Chronic Renal Failure) 06/2014 - 05/2010
1	Hyperplasia 12/2022
1	Cardiovascular Diseases (Cardiovascular Disease) 11/2022
1	Intractable Pain 10/2022
1	Chronic Pain 10/2022
1	Hereditary Spherocytosis 01/2022
1	Fibrosis (Cirrhosis) 01/2022
1	Leukocytosis (Pleocytosis) 01/2022
1	Pulmonary Arterial Hypertension 07/2021
1	Pulmonary Hypertension 07/2021
1	Bites and Stings (Sting) 01/2021
1	Pulmonary Embolism 01/2019
1	Leukemia 07/2018
1	Heart Failure 01/2018
1	Lung Diseases (Lung Disease) 01/2018
1	Obstructive Lung Diseases (Obstructive Lung Disease) 01/2018
1	Jaundice (Icterus) 01/2018
1	Thrombophilia 01/2018
1	Hypoxia (Hypoxemia) 01/2018

Drug/Important Bio-Agent (IBA)

16	Fetal Hemoglobin (Hemoglobin F)IBA 07/2018 - 08/2006
10	Hemoglobins (Hemoglobin)IBA 01/2022 - 02/2008
10	GlobinsIBA 01/2020 - 01/2005
9	Oxygen (Dioxygen)IBA 01/2022 - 12/2007
7	Hydroxyurea (Hydrea)FDA LinkGeneric 01/2021 - 07/2005
6	Biomarkers (Surrogate Marker)IBA 01/2022 - 10/2007
6	beta-Globins (beta Globin)IBA 05/2016 - 05/2005
5	IronIBA 01/2022 - 04/2010
5	Cell-Free Nucleic AcidsIBA 01/2021 - 12/2006
4	Pyruvate KinaseIBA 03/2024 - 12/2008
4	Proteins (Proteins, Gene)FDA Link 01/2022 - 02/2008
4	Sickle HemoglobinIBA 01/2020 - 01/2016
3	voxelotorIBA 06/2021 - 01/2019
3	Agammaglobulinaemia Tyrosine KinaseIBA 01/2021 - 01/2018
3	Erythropoietin FDA Link 08/2013 - 02/2011
3	BilirubinIBA 04/2013 - 07/2007
3	Ferritins (Ferritin)IBA 06/2012 - 04/2010
3	HepcidinsIBA 05/2010 - 01/2009
3	DNA (Deoxyribonucleic Acid)IBA 10/2007 - 12/2006
2	mitapivatIBA 03/2024 - 01/2022
2	Opioid Analgesics (Opioids)IBA 10/2022 - 01/2019
2	2,3-Diphosphoglycerate (2,3 Bisphosphoglycerate)IBA 01/2022 - 01/2022
2	InflammasomesIBA 01/2021 - 10/2018
2	ChemokinesIBA 01/2020 - 08/2013
2	CytokinesIBA 01/2020 - 01/2017
2	Blood Proteins (Serum Proteins)IBA 12/2018 - 01/2018
2	HMGB1 Protein (HMG1)IBA 10/2018 - 01/2018
2	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2018 - 08/2015
2	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 01/2018 - 04/2013
2	Air Pollutants (Pollutants, Air)IBA 01/2017 - 06/2009
2	Deferasirox FDA Link 10/2011 - 04/2010
1	Biotin (Vitamin H)FDA Link 04/2024
1	hemoglobin AAIBA 04/2024
1	Reticulin (Reticular Fiber)IBA 12/2022
1	CholesterolIBA 11/2022
1	HDL CholesterolIBA 11/2022
1	Ketamine FDA LinkGeneric 10/2022
1	EnzymesIBA 01/2022
1	Adenosine Triphosphate (ATP)IBA 01/2022
1	Type 5 Cyclic Nucleotide PhosphodiesterasesIBA 07/2021
1	crizanlizumabIBA 06/2021
1	Dietary IronIBA 01/2021
1	Phosphotransferases (Kinase)IBA 01/2021
1	Mitochondrial DNA (mtDNA)IBA 01/2021
1	Isoantigens (Alloantigen)IBA 01/2020
1	AntigensIBA 01/2020
1	4- ((1,4,8,11- tetraazacyclotetradec- 1- yl)methyl)benzoic acidIBA 01/2019
1	HaptoglobinsIBA 12/2018
1	Lipoproteins (Lipoprotein)IBA 01/2018
1	Carrier Proteins (Binding Protein)IBA 01/2018
1	Heme (Haem)IBA 01/2018
1	Complement C1s (C1 Esterase)IBA 01/2018
1	Bronchodilator Agents (Bronchodilators)IBA 01/2018

Therapy/Procedure

13	Therapeutics 03/2024 - 01/2005
4	Blood Transfusion (Blood Transfusions) 01/2020 - 03/2011
1	Hematopoietic Stem Cell Transplantation 04/2024
1	Stem Cell Transplantation 10/2022
1	Pain Management 10/2022
1	Tonsillectomy 01/2020
1	Arthroplasty 01/2020
1	Contraindications 01/2018